中国药科大学

邢磊，男，博士，讲师，硕士研究生导师。2005年毕业于河南大学药学院药物制剂专业，2005~2008年在河南大学药学院攻读药剂学硕士学位，其中2006.7~2008.5期间在军事医学科学院金义光课题组从事自组装药物传递系统的研究；2008年考入上海交通大学化学化工学院，师从车顺爱教授，研究方向为pH响应性配位聚合物用于药物传递的研究，主要参与《国家973项目--纳米结构材料的程序化组装》和《重大新型药物开发项目》。2012年9月加入中国药科大学药学院药剂教研室从事教学科研工作。目前已在SCI期刊上发表较高水平论文13篇。主持和参与的国家自然科学基金6项，江苏省自然基金3项。主持国重优秀青年人才基金1项。

研究方向：药用高分子材料与靶向释药系统研究；配位药物递送系统研究；聚合物药物递送系统研究

近期发表的文章：

1. Zhang BF†, Xing L†, Cui PF, Wang FZ, Xie RL, Zhang JL, Zhang M, He YJ, Lyu JY, Qiao JB, Chen BA, Jiang HL*. Mitochondria apoptosis pathway synergistically activated by hierarchical targeted nanoparticles co-delivering siRNA and lonidamine. Biomaterials. 2015, 61: 178-189. (†equal contribution)

2. Kim YK†, Zhang M†, Zhang BF, Wang FZ, Cui PF, Xie RL, Xing L*, and Jiang HL*. Hepatic Targeting Gene Delivery Using Galactosylated Ester-Based Polyspermine. J. Nanosci. Nanotechnol. 2015, doi:10.1166/jnn.2015.11341.

3. Kim YK†, Xing L†, Chen BA, Xu FG, Jiang HL*, Zhang C*. Aerosol delivery of programmed cell death protein 4 using polysorbitol-based gene delivery system for lung cancer therapy. J. Drug Target. 2014, 22(9): 829-838. (†equal contribution)

4. Xie RL†, Jang YJ†, Xing L, Zhang BF, Wang FZ, Cui PF, Cho MH*, Jiang HL*. A novel potential biocompatible hyperbranched polyspermine for efficient lung cancer gene therapy. Int. J. Pharm. 2014, 478(1): 19-30.

5. Su Z†, Xing L†, Chen Y, Xu Y, Yang F, Zhang C, Ping Q, Xiao Y*. Lactoferrin-Modified Poly(ethylene glycol)-Grafted BSA Nanoparticles as a Dual-Targeting Carrier for Treating Brain Gliomas. Mol. Pharm. 2014, 11(6): 1823-34. (†equal contribution)

6. Zheng H., Xing L, Cao Y, and Che S*, Coordination bonding based pH-responsive drug delivery systems, Coordin. Chem. Rev. 2013, 257: 1933-1944.

7. Xing L, Zheng H, Cao Y, Che S*, Coordination Polymer Coated Mesoporous Silica Nanoparticles for pH-Responsive Drug Release, Adv. Mater. 2012. 24: 6433-6437.

8.  Xing L, Cao Y, Che S*, Synthesis of Core-Shell Coordination Polymer Nanoparticles (CPNs) for pH-responsive Controlled Drug Release, Chem. Commun. 2012. 48: 5995-5997.

9. Xing L, Zheng H, Che S*, A pH-responsive Cleavage Route Based On a Metal-Organic Coordination Bonding, Chem. Eur. J. 2011, 17: 7271-7275.

10. Gao C†, Zheng H†, Xing L†, Shu M and Che S*, Designable Coordination Bonding in Mesopores as a pH-Responsive Release System, Chem. Mater. 2010, 22: 5437-5444. (†equal contribution)

11. Li C, Xing L and Che S*, Coordination Bonding Based pH-Responsive Albumin Nanoparticles for Anticancer Drug Delivery, Dalton T. 2012, 41: 3714-3719.

12. Ma Y, Xing L, Zheng H and Che S*, Anionic-Cationic Switchable Amphoteric Monodisperse Mesoporous Silica Nanoparticles, Langmuir, 2011, 27: 517-520.

13. Jin Y*, Xing L, Tian Y, Li M, Gao C, Du L, Dong J* and Chen H, Self-assembled drug delivery systems. Part 4. In vitro/in vivo studies of the self-assemblies of cholesteryl-phosphonyl zidovudine. Int. J. Pharm. 2009, 345: 40-48.

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